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Pre-implantation Genetic Testing (PGT)

Advanced embryo genetic testing to improve IVF success and reduce inherited risks.

What is PGT?

Pre-implantation Genetic Testing (PGT) is performed on embryos created through IVF to identify genetic or chromosomal abnormalities before implantation. This helps optimise embryo selection and improve clinical outcomes.

PGT-A

Testing for chromosomal aneuploidies to improve implantation and live-birth rates.

  • AI-enhanced aneuploidy detection
  • Better embryo selection
  • Lower miscarriage risk

PGT-M

Testing embryos for single-gene disorders in families with known genetic diseases.

  • Custom assay design
  • Mutation-specific testing
  • Prevents inherited conditions

PGT-SR

For parents with chromosomal structural rearrangements (e.g., translocations).

  • Detects unbalanced rearrangements
  • Improves viability
  • Reduces miscarriage risk

PGT-HLA

Embryo HLA typing to identify compatible donors for affected siblings.

  • Tissue compatibility matching
  • Used for “saviour sibling” care
  • Performed with PGT-A/M

PGT-A Plus

PGT-A Plus offers advanced embryo screening beyond standard aneuploidy testing.

  • Detects triploidies
  • uniparental disomy (UPD)

Molecular PN Check

Molecular PN Check confirms the genetic identity of embryos at the pronuclear stage before biopsy.

  • Confirms 0/2/3 PN
  • Ensures accurate tracking
  • Eliminates the risk of sample mix-up

Parental Check

Embryo parental check ensures accurate matching of embryos to intended parents before genetic testing.

  • Safeguards identity
  • Confirms lineage
  • Maintains the integrity of the PGT process

PGT-Pre-Clinical Workup

PGT pre‑clinical workup establishes parental genotypes and validates informative markers for embryo testing.

  • Pre-requisite for PGT-M or PGT-SR
  • Takes 4 weeks
  • Parental blood samples are used

How PGT Works

All PGT types follow a structured workflow supporting both clinicians and patients:

Considerations & Limitations

While highly informative, PGT has certain limitations and contextual factors:

Interested in PGT testing?

Speak with our technical team to determine the most suitable PGT option.

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