Test Code: PNL230

Genes: EPCAM, FH, FLCN, HNF1A, HNF1B, MET, MITF, MLH1, MSH2, MSH6, PMS1, PMS2, PTEN, SDHB, SDHD, TSC1, TSC2, VHL, WT1 (19 genes)

Sample Type: 3 ml peripheral blood in EDTA (purple/pink top) tube

Method: Capture-based target enrichment and Next Generation Sequencing

Turnaround Time: 3 weeks

Courier: Ship overnight at room temperature to receive next day. Do not refrigerate or freeze. Maintain specimen at room temperature.

Price: 1800

Description:
The Renal Cancer 19 - Gene Panel screens for mutations in genes linked to hereditary RCC syndromes. It covers major syndromes such as VHL, Birt-Hogg-Dube', hereditary papillary RCC, tuberous sclerosis, Cowden, Li-Fraumeni, and FH-related RCC, as well as rarer predisposition genes. This panel is crucial for diagnosis, risk stratification, and family counseling in unexplained or familial renal cancer.